. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: Biotechnol J. 2015 Sep 10;10(10):1529–1545. doi: 10.1002/biot.201400758

Table 1.

Combinations of cell surface markers to identify discrete human vs. mouse hematopoietic stem and progenitor populations.

	Human	Mouse
HSPC	Lin⁻CD34 ⁺CD38 ⁻	Lin⁻Sca-1 ⁺c-Kit ⁺(LSK; 0.05% of BM)
HSC	Lin⁻CD34 ⁺CD38 ⁻CD90 ⁺CD45RA ⁻	Lin⁻ Sca-1⁺ c-Kit⁺Flk2 ⁻CD34 ⁻Slamf1 ⁺
MPP	Lin⁻CD34 ⁺CD38 ⁻CD90 ⁻CD45RA ⁻	Lin⁻ Sca-1⁺ c-Kit⁺Flk2 ⁺CD34 ⁺
CLP	Lin⁻CD34 ⁺CD38 ⁺CD10 ⁺	Lin⁻Flk2 ⁺IL7R α⁺CD34 ⁺
CMP	Lin⁻CD34 ⁺CD38 ⁺IL3R α^lowCD45RA ⁻	Lin⁻ Sca-1⁻ c-Kit⁺ FcγII/IIIR^loCD34⁺
MEP	Lin⁻CD34 ⁺CD38 ⁺IL3R α⁻CD45RA ⁻	Lin⁻ Sca-1⁻ c-Kit⁺ FcγII/IIIR⁻CD34⁻
GMP	Lin⁻CD34 ⁺CD38 ⁺IL3R α⁺CD45RA ⁻	Lin⁻ Sca-1⁻ c-Kit⁺ FcγII/IIIR^hiCD34⁺

MPP, multipotent progenitor; CLP, common lymphoid progenitor; CMP, common myeloid progenitor; MEP, megakaryocyte-erythrocyte progenitor; GMP, granulocyte-macrophage progenitor. Information adapted from [17, 186–188].