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. Author manuscript; available in PMC: 2016 Nov 9.
Published in final edited form as: Cancer Cell. 2015 Oct 29;28(5):638–652. doi: 10.1016/j.ccell.2015.09.022

Figure 1. Tumor antigen expression in murine and human PDA.

Figure 1

(A) Immunohistochemical analyses of target antigens in murine and human (hPDA) tissues. d, duct; ac, acini; i, islets; arrows, high expression; arrowheads, low-moderate expression; *, tumor epithelial cells. Scale bar, 25 μm.

(B) Immunofluorescence for MSLN and cytokeratin (CK) in indicated KPC tissues. Arrows, MSLN+CK+ cells. Scale bar, 25 μm.

(C) FACs plot of MSLN, MHC I and p53 in early passage (<3X) primary KPC PDA cells.

(D) Relative expression of indicated mRNAs in primary KPC PDA cells. Each point represents an independent cell preparation. Mean ± SEM.

(E) Immunoblot analyses of primary murine pancreatic ductal cells, primary preinvasive KC cells (Pre) and two independent invasive KPC PDA primary cell preparations.

See also Figure S1.

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