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. Author manuscript; available in PMC: 2016 Jan 24.
Published in final edited form as: Neurobiol Aging. 2009 Dec 24;32(3):548.e9–548.18. doi: 10.1016/j.neurobiolaging.2009.11.021

Table 3.

Summary effect estimates and confidence interval for Omi/HtrA2 gene.

SNP Overall Het. P (I2) Scandinavian Age at examination*



Sites RE OR (95% CI) FE OR (95% CI) RE OR (95% CI) FE OR (95% CI) Het. P (I2) RE OR (95% CI) FE OR (95% CI) Het. P (I2)
rs72470544 13 0.98(0.77–1.26) 1.02(0.84–1.22) 0.17(28%) 1.27(0.63–2.56) 1.45(0.97–2.15) 0.20(39%) 0.96(0.72–1.27) 0.96(0.72–1.27) 0.35(9%)
rs10779958 20 0.99 (0.93–1.06) 0.99(0.93–1.06) 0.41(3%) 1.02(0.82–1.27) 1.03(0.85–1.25) 0.33(9%) 1.03(0.91–1.16) 1.03(0.92–1.17) 0.56(0%)
rs2231250 17 1.01(0.94–1.09) 1.02(0.94–1.09) 0.49(0%) 1.03(0.79–1.34) 1.07(0.87–1.30) 0.27(24%) 1.02(0.91–1.16) 1.03(0.91–1.16) 0.56(0%)
rs1183739 14 1.03(0.93–1.13) 1.04(0.96–1.12) 0.20(23%) 1.01(0.83–1.23) 1.01(0.83–1.23) 0.39(0%) 1.17(1.031.33) 1.17(1.031.33) 0.76(0%)
rs2241028 18 1.07(0.99–1.17) 1.08(0.99–1.17) 0.58(0%) 1.41(1.021.94) 1.41(1.021.94) 0.90(0%) 1.05(0.76–1.44) 1.01(0.81–1.26) 0.18(36%)

FE, fixed effects; RE, random effects; CI, confidence interval; Het., heterogeneity (Q statistic); (*) age at examination <65 years; bold: p < 0.05.