(A) Distribution of the MPs in the mouse brain after local administration in the U87 glioma-bearing mice with and without MF treatment. After MF treatment, the brain sections were stained with H&E. MPs are seen as black dots in the tissue. Quantification of the MPs distribution in the non-tumor (B) and tumor area (C). MPs are mainly found in the brain tumor. Data are presented as Mean±SE (n=3 mice per group). (D) Biodistribution of the MPs after MF treatment. Mouse tissue samples including liver, spleen, heart, lungs, large intestine, kidney, bladder and testes were stained with H&E. No MPs were found in these organs.