Table 4.

Association of demographic and OA factors with a meaningful decline in walking (< 7,000 steps/day at follow up and ≥ 20% decline in steps/day). Bold indicates statistical significance was met.

		% (n/N) with a meaningful decline in walking	Un-adjusted Risk Ratio for a meaningful decline in walking [95% CI]	Adjusted Risk Ratio for a meaningful decline in walking [95% CI]
ROA	Absent	15.7 (45/286)	Reference	Reference1
	Present	19.1 (57 (298)	1.2 [0.9, 1.7]	1.1 [0.8, 1.6]
Consistent frequent knee pain	Absent	14.8 (62/420)	Reference	Reference2
	Present	24.5 (40/163)	1.7 [1.2, 2.4]	1.5 [1.0, 2.2]
ROA Worsening	Absent	14.3 (51/356)	Reference	Reference1
	Present	22.4 (51/228)	1.6 [1.1, 2.2]	1.4 [1.0, 1.9]
Pain Worsening	Absent	17.3 (26/150)	Reference	Reference2
	Present	17.5 (76/434)	1.0 [0.7, 1.5]	0.8 [0.5, 1.2]
Obesity (BMI kg/m2)	< 30	12.2 (45/370)	Reference	Reference2
	≥ 30	26.6 (57/214)	2.2 [1.5, 3.1]	2.1 [1.5, 3.1]
Depressive Symptoms	Absent	16.4 (91/555)	Reference	Reference2
	Present	37.9 (11/29)	2.3 [1.4, 3.8]	2.0 [1.1, 3.7]
Fatigue	Absent	16.4 (71/433)	Reference	Reference2
	Present	23.5 (31/151)	1.3 [0.9, 1.8]	0.8 [0.5, 1.2]
Living situation	Lives with spouse/others	18.4 (14/76)	Reference	Reference2
	Lives Alone	17.3 (88/508)	1.1 [0.6, 1.8]	0.9 [0.5, 1.5]
Catastrophizing	Absent	15.0 (47/313)	Reference	Reference2
	Present	20.3 (55/271)	1.4 [1.0, 1.9]	1.1 [0.8, 1.6]
Widespread pain	Absent	15.7 (60/383)	Reference	Reference2
	Present	20.1 (42/201)	1.3 [0.9, 1.9]	1.1 [0.7, 1.6]
Comorbidity	None	14.4 (59/409)	Reference	Reference2
	≥ 1	24.6 (43/175)	1.7 [1.2, 2.4]	1.4 [1.0, 2.1]

¹Adjusted for potential confounders including race, education, and study site, and mutually adjusted for other exposures except for consistent frequent knee pain

²Adjusted potential confounders including race, education, and study site and mutually adjusted for other exposures