Figure 3. Tuba1aND/ND embryos have defects in motor axon outgrowth.
(A,B) Axial motor neuron axon extension from the spinal cord in E14.5 Tuba1aND/+ and Tuba1aND/ND embryos expressing Mnx1-eGFP. (C) Quantification of axial motor axon extension in E14.5 and E18.5 Tuba1aND/+ and Tuba1aND/ND embryos. Asterisks indicate significant difference, by t-test (p < 0.05). (D,E) Limb motor neuron axon extension into the distal limb in E14.5 Tuba1aND/+ and Tuba1aND/ND embryos. (F) Quantification of limb motor axon extension in Tuba1aND/+ and Tuba1aND/ND embryos at E14.5 and E18.5. (G,H) Limb motor axon extension at E18.5 in Tuba1aND/+ and Tuba1aND/ND embryos.