. Author manuscript; available in PMC: 2017 Mar 1.

Published in final edited form as: Mult Scler. 2015 Jul 24;22(3):362–372. doi: 10.1177/1352458515590646

Table 3.

Estimated rates of change in GCIP thickness over the first 8 months of follow-up after AON.

Time interval after AON	Group	Rate of change (μm/month)	95% CI	P-value	P-value comparing rates in affected vs. fellow eyes	P-value comparing rates in affected vs. control eyes
Baseline to 4 months	Affected eyes	-2.52	-2.9, -2.2	<0.001	<0.001	<0.001
	Fellow eyes	-0.15	-0.5, 0.2	0.411	<0.001
	Control eyes^*	-0.004	-0.6, 0.6	0.988	-
4 to 8 months	Affected eyes	-0.004	-0.3, 0.3	0.978	0.928	0.955
	Fellow eyes	-0.02	-0.3, 0.3	0.878	0.928
	Control eyes^*	0.02	-0.6, 0.7	0.946	-

Randomly-selected, single eye per control.

Abbreviations: AON = acute optic neuritis; GCIP = ganglion cell + inner plexiform layers; CI = confidence interval.