. Author manuscript; available in PMC: 2017 Mar 1.

Published in final edited form as: Mult Scler. 2015 Jul 24;22(3):362–372. doi: 10.1177/1352458515590646

Table 4.

Estimated rates of change in INL+OPL thickness over the first 8 months of follow-up after AON.

Time interval after AON	Group	Rate of change (μm/month)	95% CI	P-value	P-value comparing rates in affected vs. fellow eyes	P-value comparing rates in affected vs. control eyes
Baseline to 4 months	Affected eyes	0.42	0.2, 0.6	<0.001	0.243	0.341
	Fellow eyes	0.24	0.03, 0.5	0.027	0.243
	Control eyes^*	0.21	-0.2, 0.6	0.269	-
4 to 8 months	Affected eyes	-0.17	-0.4, 0.01	0.067	0.550	0.847
	Fellow eyes	-0.09	-0.3, 0.1	0.339	0.550
	Control eyes^*	-0.13	-0.5, 0.3	0.513	-

Randomly-selected, single eye per control.

Abbreviations: AON = acute optic neuritis; INL = inner nuclear layer; OPL = outer plexiform layer; CI = confidence interval.