Table 1.

Baseline parameters.

fcyt = 0.83

fER = 0.17

gIP3R = 120400.0 molecules/mM/ms

kIP3 = 0.00013 mM

kact = 0.0004 mM

kinh = 0.0019 mM

gleak = 18.06 molecules/mM/ms

gserca = 1.9565 molecules/ms

kserca = 0.0001 mM

τIP3 = 1000 ms

τIP3R = 400 ms

τex = 5 ms

D${\mathrm{Ca}}_{\mathrm{cyt}}^{2+}$ = 0.08 μm2/ms

D${\mathrm{Ca}}_{\mathrm{ER}}^{2+}$ = 0.08 μm2/ms

DIP3 = 1.415 μm2/ms

DB = 0.043 μm2/ms

DCaB = 0.043 μm2/ms

FRate = 5ms−1mM−1

BRate = 9.5 × 10−4ms−1