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. 2015 Nov 29;6(1):64–70. doi: 10.1016/j.apsb.2015.10.001

Table 5.

Assessment of dose proportionality of J10688 based on power model.

Parameter Acceptance range β1 90% Confidence interval
AUC0–t 0.9031–1.0969 0.8456 0.7204–0.9708
AUC0–∞ 0.9031–1.0969 0.8407 0.7206–0.9608
C0 0.8451–1.155 0.6752 0.5083–0.8422

β1: the slopes of lnAUC0–t, lnAUC0–∞ and lnC0 to lnDose.