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. 2016 Jan 25;7:13. doi: 10.3389/fmicb.2016.00013

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Copyright © 2016 Gonçalves and de Carvalho.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inducing persister formation in Staphylococcus aureus. (A) Growth curve of normal cells in MHB. (B) Time-dependent killing curve during exposure to 50 and 100 mg/L of vancomycin (V) and teicoplanin (T). The CFU/mL data are represented in logarithm scale. (C) Growth curves of S. aureus in fresh MHB after exposure to 50 (C1) and 100 (C2) mg/L vancomycin for 3, 4, 5, 6, 8, 16, and 24 h. (D) Growth curves of S. aureus in fresh MHB after exposure to 50 (D1) and 100 (D2) mg/L teicoplanin for 3, 4, 5 and 6, 8, 16, and 24 h. Error bars represent standard deviation values.