Figure 9.

Population decomposition of LFP signals with MUA-based firing-rate estimates. Results from fitting gLPA-1 (K = 1; Equation 2) to LFP data for a time segment where the network is driven by 12.5 Hz oscillatory input in the thalamic relay cells with MUA-based firing-rate estimates, cf. Figure 8. (A) Comparison of ground-truth LFP (“true” LFP; top) with LPA prediction (middle) with difference shown in bottom panel. (B–E) Estimated contributions from the four laminar components (color plots) with spatial profiles ($L_n^1$) shown left and temporal profiles [black:$R_n(t)=h^1\otimes r_n$] below. Fitted parameters: Δ₁ = 0.63 ms, τ₁ = 12.65 ms. To facilitate comparison with LPA decomposition results from using ground-truth firing rates depicted in Figure 2 (green spatial and temporal profiles), the time-convolved firing rates R_n(t) are scaled to have a maximum value of one in the depicted time interval, while $L_n^1$ is scaled correspondingly to keep the product $L_n^1·R_n(t)$ fixed.