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. Author manuscript; available in PMC: 2016 Jan 25.
Published in final edited form as: Med Chem (Los Angeles). 2014;4(11):722–724. doi: 10.4172/2161-0444.1000219

Table 1.

Clotrimazole as a drug of interest against several diseases.

Disease Mechanism of action
Sickle cell disease [2] Inhibition of calcium-dependent potassium channel
Malaria [4] Heme-induced membrane damage
Chagas disease [5], Candida albicans [7], Tineapedis (Athlete's foot) [6] Inhibition of ergosterol synthesis
Cancer [13] Inhibition of calcium-dependent potassium channel, glycolytic enzymes, and G1-phase arrest