Table 2.

Potential correlates of neutrophil antimycobacterial activity

Correlate		Mean Ratio of Luminescence in Neutrophil Samples vs. Serum Controls at 1 h	Univariate P Value	Mean Ratio of Luminescence in Neutrophil Samples vs. Serum Controls at 24 h	Univariate P Value
Sex	Male	0.79	0.52	0.75	0.53
	Female	0.83		0.78
BCG	Yes	0.80	0.68	0.77	0.93
	No	0.88		0.73
	Unsure/unclear	0.81		0.78
IGRA	Positive	0.79	0.42	0.73	0.16
	Negative	0.83		0.79
Smoking	Yes	0.75	0.29	0.69	0.18
	No	0.83		0.78
Regular alcohol	Yes	0.89	0.11	0.79	0.54
	No	0.79		0.76
Comorbidity	Yes	0.79	0.54	0.74	0.47
	No	0.83		0.78
HIV status	Positive	0.88	0.01	0.82	0.01
	Negative	0.76		0.71
		Pearson r (correlation with ratio of luminescence in neutrophil samples vs. serum controls at 1 h)
Age		0.02	0.90	0.17	0.31
Weight		−0.33	0.04	−0.12	0.94
Serum C-reactive protein		−0.28	0.09	−0.08	0.64

Definition of abbreviations: BCG = Mycobacterium bovis–Bacille Calmette-Guérin; IGRA = IFN-γ release assay.

Bold type indicates statistical significance (P < 0.05).