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. 2015 Nov;12(11):1646–1653. doi: 10.1513/AnnalsATS.201507-408OC

Table 3.

Therapeutic alliance and its relationship to key patient, caregiver, and clinician factors: exploratory regression modeling results

  Therapeutic Alliance, Unadjusted, Mean (SD)* P Value Regression Model β (95% CI) P Value
Patient age, yr   0.046
 <55 55 (7)      
 ≥55 51 (7)      
Patient Charlson Comorbidity Index score   0.009 4.74 (2.29–7.18) <0.001
 <2 Comorbidities 55 (6)      
 ≥2 Comorbidities 49 (7)      
Patient APACHE II score   0.033
 <20 54 (6)      
 ≥20 50 (9)      
Caregiver social support   0.001
 High 55 (6)      
 Low 48 (8)      
Caregiver report that treatment reflected patient wishes   0.004
 Yes 55 (5)      
 No or unsure 50 (8)      
Caregiver trust in ICU team   <0.001 4.43 (1.70–7.18) 0.002
 High 56 (4)      
 Low 47 (8)      
Caregiver report of conflict with ICU team   0.045
 Low or none 55 (6)      
 Moderate or high 51 (8)      
Caregiver report of quality of communication   <0.001 5.97 (2.76–9.2) <0.001
 High 55 (5)      
 Low 44 (7)      
Caregiver report of decisional conflict   0.001 4.21 (0.95–7.47) 0.012
 Low 54 (6)      
 High 46 (8)      

Definition of abbreviations: APACHE = Acute Physiology and Chronic Health Evaluation; CI = confidence interval; HADS = Hospital Anxiety and Depression Scale; HCS = Human Connection Scale; ICU = intensive care unit; PTSS = post-traumatic stress scale.

*

Relationship between HCS score and variable; P value from paired t tests. Variables not included in modeling because HCS–variable r < 0.2: caregiver age, faith, health literacy, active coping use, caregiver burden, caregiver quality of life, HADS anxiety score, HADS depression score, HADS total score, and PTSS score.

Relationship between HCS score and key variables using stepwise regression model adjusted for variables shown; constant = 44.05 (40.73–47.37), P < 0.001.