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. 2004 Feb 1;10(3):327–331. doi: 10.3748/wjg.v10.i3.327

Table 2.

Inhibition of tc-LIGRLO, SLIGKV, trypsin, anti-IgE or calcium ionophore A23187 (CI) induced tryptase release from colon mast cells by pertussis toxin (1 µg/mL) and metabolic inhibitors

Concentration of stimulus % inhibition of tryptase release
Pertussis toxin Metabolic inhibitors
tc-LIGRLO 100 µmol/mL 85 ± 9.6a 91 ± 9.3a
SLIGKV 100 µmol/mL 91 ± 4.8a 85 ± 9.6a
Trypsin 10 µg/mL 100 ± 0a 91 ± 3.9a
Anti-IgE 10 µg/mL 87 ± 10a 94 ± 3.6a
CI 1.0 µg/mL 84 ± 8.8a 95 ± 4.0a

The values shown are mean ± SEM for four separate experiments performed in duplicate.

a

P < 0.05 compared with the uninhibited control group (paired Student’s t test).