Table 1.
Patients’ characteristics in three groups (mean ± SD)
| Characteristics | Cholangiocarcinoma | Benign biliary diseases | Healthy individuals |
| N | 35 | 92 | 15 |
| Age (yr) | 60.37 ± 11.2 | 49.78 ± 10.6 | 27.6 ± 4.7 |
| Sex (M/F) | 19/16 | 39/53 | 15/0 |
| Total bilirubin (umol/L) | 47.4 ± 2.1a | 8.3 ± 0.7 | 8.6 ± 0.9 |
| AST (U/L) | 79 ± 21.2a | 26 ± 3.5 | 21 ± 4.6 |
| ALP (U/L) | 193 ± 41.8a | 114 ± 50.6 | 90 ± 18.3 |
| CA19-9 (KU/L) | 290.31 ± 5.34bc | 13.38 ± 2.59 | 12.78 ± 3.69 |
| CEA (μg/L) | 36.46 ± 18.03a | 13.84 ± 3.85 | 11.48 ± 3.37 |
a
P < 0.05, bP < 0.001 vs benign biliary diseases or healthy individuals. cP < 0.05 vs serum CEA. AST = aspartate aminotranferase, ALP = alkaline phosphatase, CA19-9 = carbohydrate antigen 19-9, CEA = carcinoembryonic antigen.