FIG 4 .

Assessment of the role of host RBPs on vRNA levels. Huh7 cells were transfected with nonsilencing (NS) control siRNA or siRNA pools containing 4 unique siRNAs per target. Cells were infected with DENV 48 h posttransfection at an MOI of 1. Total cell-associated RNA was harvested 24 h postinfection, and levels of v RNA accumulation were measured by RT-qPCR using primers that amplify a region in the middle of the viral coding sequence (ORF) or in the 3′ UTR. Statistical significance measured by Student’s t test: *, P ≤ 0.05.