Table 4.
Concentrations of cytokines in gastric mucosa of children examined depending on inflammation stage according to Sydney System[25]
| Cytokines |
Fa |
Hp |
Fa+Hp |
|||||||
| (pg/mg of the protein) |
Antrum |
Corpus |
Antrum |
Corpus |
Antrum |
Corpus |
||||
| Mild+moderate | Mild+moderate | Mild+moderate | Severe | Mild | Moderate+severe | Mild+moderate | Severe | Mild | Moderate+severe | |
| IL-2 | 17.7 | 17.9 | 184.4b | 38.8 | 77.7 | 150.4b | 125.4b | 38.3 | 106.7 b | 98.6 |
| IFN-γ | 54.9 | 46.6 | 13.1b | 24.1 | 17.8b | 19.7b | 21.9 | 34.3 | 23.1 | 27.1 |
| IL-4 | 15.4 | 6.7b | 62.2b | 3.9a | 37.6 | 32.7 | 44.3 | 1.7 | 32.1 | 46.4 |
| IL-5 | 24.5 | 25.5 | – | – | – | – | 29.7 | – | – | 33 |
| IL-8 | 37.5 | 37.5 | 101.2 | 72.9 | 93.6 | 83.1 | 98 | 108.2 | 71.1 | 118.3 |
| IL-10 | 30.4 | 24.4 | – | – | – | – | 44.6 | – | – | 58.9 |
| TNF-α | 20.6 | 4.8 | 65.2 | 24.1 | 48.7 | 43.3 | 54.8b | 24.3 | 49 | 44.8 |
P<0.01, cytokine concentrations statistically significantly different from controls. Fa, food allergy; Hp, H pylori; C, control group.