Table 5.
Cytokine concentrations in gastric mucosa of children examined depending on the inflammation activity according to Sydney System[25]
| Cytokines (pg/mg protein) |
Fa |
Hp |
Fa+Hp |
|||||||
|
Antrum |
Corpus |
Antrum |
Corpus |
Antrum |
Corpus |
|||||
| Mild+moderate | Mild+moderate | Mild+moderate | Severe | Mild+moderate | Severe | Mild+moderate | Severe | Mild | Moderate+severe | |
| IL-2 | 17.7 | 17.9 | 204.3b | 72.5 | 69 | 187.6b | 70.1 | 110.9 | 119.3 | 74.3 |
| IFN-γ | 54.9 | 46.6 | 20.4 | 18.4 | 21.8b | 14.6b | 25.6 | 25.4 | 22.4 | 33.4 |
| IL-4 | 15.4 | 6.7b | 81.1b | 6.7b | 30 | 47.8 | 52 | 29.8 | 39.9 | 39.9 |
| IL-5 | 24.5 | 25 | – | – | – | – | – | – | – | – |
| IL-8 | 37.5 | 37.5 | 83.5 | 90.2 | 86.9 | 89.6 | 69.8 | 115.5 | 83.2 | 131.6 |
| IL-10 | 30.4 | 24 | – | – | – | – | – | – | – | – |
| TNF-α | 20.6 | 4.8 | 76 | 33.3 | 37.4 | 57.9 | 24.6 | 54.6 | 60.4 | 24.9 |
P<0.01 vs cytokine concentrations statistically significantly different from controls. Fa, food allergy; Hp, H pylori; C, control group.