Table 3.
Average long-axis (LAX) systolic and diastolic strain echocardiographic characteristics.
Baseline
|
Week 1
|
Week 3
|
Week 6
|
|||||
---|---|---|---|---|---|---|---|---|
Control | Diabetic | Control | Diabetic | Control | Diabetic | Control | Diabetic | |
LAX strain measurements in systole | ||||||||
Longitudinal strain (%) | − 20.2 ± 0.9 | − 21.4 ± 2.6 | − 17.9 ± 0.6 | − 16.7 ± 0.9 | − 19.3 ± 1.0 | − 18.5 ± 0.3 | − 18.4 ± 1.2 | − 18.7 ± 1.0 |
Longitudinal SR (1/s) | − 8.3 ± 0.6 | − 7.5 ± 0.3 | − 7.1 ± 0.3 | − 6.7 ± 0.2 | − 8.3 ± 0.3 | − 6.8 ± 0.1* | − 8.5 ± 0.6 | − 6.8 ± 0.4* |
Longitudinal velocity (cm/s) | 0.9 ± 0.06 | 0.9 ± 0.08 | 0.8 ± 0.04 | 0.9 ± 0.03 | 1.0 ± 0.05 | 0.9 ± 0.01 | 0.9 ± 0.05 | 0.9 ± 0.05 |
Longitudinal displacement (mm) | 0.2 ± 0.02 | 0.2 ± 0.03 | 0.2 ± 0.01 | 0.2 ± 0.01 | 0.2 ± 0.02 | 0.2 ± 0.01 | 0.2 ± 0.02 | 0.2 ± 0.03 |
Radial strain (%) | 28.8 ± 2.4 | 26.9 ± 3.0 | 27.8 ± 1.2 | 22.0 ± 1.1* | 30.1 ± 2.0 | 24.7 ± 1.0* | 27.7 ± 2.0 | 22.0 ± 0.6* |
Radial SR (1/s) | 8.6 ± 0.8 | 8.1 ± 0.4 | 8.1 ± 0.2 | 6.7 ± 0.2* | 8.6 ± 0.4 | 6.9 ± 0.3* | 7.6 ± 0.2 | 6.3 ± 0.3* |
Radial velocity (cm/s) | 1.5 ± 0.09 | 1.5 ± 0.1 | 1.3 ± 0.04 | 1.1 ± 0.04* | 1.5 ± 0.08 | 1.2 ± 0.05* | 1.4 ± 0.01 | 1.2 ± 0.05* |
Radial displacement (mm) | 0.5 ± 0.02 | 0.5 ± 0.04 | 0.5 ± 0.01 | 0.4 ± 0.01* | 0.5 ± 0.02 | 0.5 ± 0.01 | 0.5 ± 0.01 | 0.4 ± 0.02 |
Long-axis strain measurements in diastole | ||||||||
Longitudinal strain (%) | 2.3 ± 0.4 | 2.4 ± 1.0 | 1.3 ± .02 | 1.3 ± 0.3 | 1.1 ± 0.2 | 1.6 ± 0.3 | 1.1 ± 0.2 | 0.9 ± 0.1 |
Longitudinal SR (1/s) | 11.4 ± 0.7 | 11.5 ± 1.0 | 7.3 ± 0.2 | 7.9 ± 0.6 | 8.9 ± 0.6 | 9.8 ± 0.6 | 8.8 ± 0.6 | 10.0 ± 1.0 |
Longitudinal velocity (cm/s) | − 1.0 ± 0.08 | − 1.1 ± 0.05 | − 0.9 ± 0.01 | − 1.0 ± 0.06 | − 1.0 ± 0.05 | − 0.9 ± 0.08 | − 0.9 ± 0.06 | − 1.0 ± 0.05 |
Longitudinal displacement (mm) | − 0.03 ± 0.01 | − 0.04 ± 0.008 | − 0.03 ± 0.004 | − 0.04 ± 0.008 | − 0.02 ± 0.005 | − 0.04 ± 0.005 | − 0.02 ± 0.006 | − 0.04 ± 0.008 |
Radial strain (%) | − 2.8 ± 0.4 | − 2.4 ± 0.5 | − 1.6 ± 0.1 | − 2.1 ± 0.3 | − 1.6 ± 0.3 | − 2.0 ± 0.3 | − 2.1 ± 0.6 | − 1.9 ± 0.4 |
Radial SR (1/s) | − 10.9 ± 1.1 | − 10.5 ± 0.5 | − 9.9 ± 0.6 | − 9.1 ± 0.7 | − 10.2 ± 0.6 | − 10.2 ± 0.6 | − 10.0 ± 0.4 | − 10.3 ± 0.5 |
Radial velocity (cm/s) | − 2.0 ± 0.1 | − 2.0 ± 0.1 | − 1.5 ± 0.04 | − 1.4 ± 0.08 | − 1.6 ± 0.1 | − 1.6 ± 0.1 | − 1.6 ± 0.05 | − 1.6 ± 0.09 |
Radial displacement (mm) | − 0.01 ± 0.002 | − 0.008 ± 0.002 | − 0.01 ± 0.001 | − 0.01 ± 0.002 | − 0.02 ± 0.003 | − 0.01 ± 0.003 | − 0.02 ± 0.004 | − 0.02 ± 0.003 |
Values are shown as means ± SEM. SR = strain rate.
P< 0.05 Control versus Diabetic in a given week. 2-tailed Student’s t test. Control n = 8, Diabetic n = 8.