Fig. 8.
Experiments showing voltage change that occurred in PD neurons with 2.5 M KAc and squid fill and stimulation every 2 min for 1 h. Initial voltage for the 2.5 M KAc cell is −46 mV and for the squid cell is −50 mV. A: raw data. Squid Vm shows only a slow, small hyperpolarization throughout the experiment. The 2.5 M fill neuron began to hyperpolarize sharply after ∼8 min (arrow). At ∼12 min, the cell “bottomed out” and began to depolarize, which continued for the remainder of the experiment. B: time expansion of data in rectangle in A showing stimulation protocol.