Table 1.
First author (year) [reference] | Country (ethnicity) | Spontaneous resolution | Persistent infection | Matching | Anti-HCV tests | HLA typing |
Alric (1997) | France (European) | 25, M/F: 9/16 | 103, M/F: 58/45 | Sex, age, source of HCV infection, HCV-serotype | 2G EIA and RIBA | PCR-SSOP |
[21] | Age: 40.6±15.7 yr | Age: 45.4±12.4 yr | ||||
Cramp (1998) | UK (European) | 49, M/F: 30/19 | 55, M/F: 31/24 | Sex, age, source of HCV infection and duration | 2G line immunoassay | PCR-SSOP |
[22] | Duration: 15.5 (3-42) yr | Duration: 14.2 (2-40) yr | ||||
Minton (1998) | UK (European) | 35, M/F: 19/16 | 138, M/F: 87/51 | Sex, age, source of HCV infection | 2G ELISA and RIBA | PCR-SSOP |
[23] | Age: 37.9±10.8 yr | Age: 37.2±10.1 yr | ||||
Mangia (1999) | Italy (European) | 35 | 149 | Sex, HCV-serotype, not age, | RIBA and 3G EIA | PCR-SSP |
[24] | not duration | |||||
Thursz (1999) | European | 85, M/F: 37/48 | 170, M/F: 74/96 | Sex, center, not age | ELISA and RIBA | PCR-SSP |
[25] | Age: 45±14 yr | Age: 50±16 yr | ||||
Vejbaesya (2000) | Thailand (Asian) | 43 Blood donor | 57 | Sex | 2G EIA and RIBA | PCR-SSOP |
[26] | M/F: 25/18 | M/F: 31/18 | ||||
Alric (2000) | France (European) | 63, M/F: 21/42 | 282, M/F: 150/132 | Age, source of HCV infection and duration, not sex | 2G EIA and RIBA | PCR-SSOP |
[27] | Age: 42.1±15.4 yr | Age: 46±12.3 yr | ||||
Fanning (2000) | Irish (European) | 85 Female | 72 Female | From single source | RIBA | Reverse line probe hybridization |
[13] | ||||||
Thio (2001) | North America | 200, M/F: 166/34 | 374, M/F: 310/64 | Age, sex, race | 2G EIA and RIBA | PCR-SSP PCR-SSCP |
[28] | Age: 25.7 yr | Age: 27.8 yr | ||||
Azocar (2003) | Hispanic (European) | 40,M/F: 33/7 | 72, M/F: 54/18 | Age, sex | EIA and RIBA | PCR-SSOP PCR-SSP |
[29] | Age: 37.9 yr | Age: 39.2 yr | ||||
Spada (2004) | Italy (European) | 10, M/F: 5/5 | 24,M/F:22/2 | Not sex, age, source of HCV infection, HCV-serotype | 3G ELISA and RIBA | PCR-SSP |
[30] | Age: 40.5 (20-61) yr | Age: 29 (20-56) yr |
EIA: enzyme-immunoassay; RIBA: recombinant immunoblot assay; ELISA: enzyme-linked-immunosorbent assay; 2G: second generation; 3G: third generation; SSOP: sequence-specific oligonucleotide probes; SSP: sequence specific primers; SSCP: single stranded conformational polymorphisms.