Kaplan-Meier survival curves for STEC O157 carriage by cattle. Colonization was determined by RAJ swab culture for each of four seasonal trials (HS [high dose, summer], HW [high dose, winter], LS [low dose, summer], and LW [low dose, winter]). Animals were considered colonized until they were culture negative for STEC O157 on two sequential sampling dates. A trend toward more prolonged shedding during the winter months at each dose level was not statistically significant (P = 0.058).