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. Author manuscript; available in PMC: 2016 Jan 25.
Published in final edited form as: J Biomol Screen. 2010 Apr 22;15(5):498–507. doi: 10.1177/1087057110368294

Fig. 6.

Fig. 6

Pilot screening of a marine-derived natural product library using the optimized TRPM7 assay. (A) TRPM7-HEK293 cells were preincubated with vehicle (positive control; n = 66) or microbial extracts (100 µg/mL; n = 420). WT-HEK293 cells were preincubated with vehicle (negative controls; n = 48). The Z′ factor was calculated from pooled normalized controls (± SD), and collective normalized extract responses were similar to positive controls and were used to calculate the Z factor. (B) Well-by-well pooled normalized extract responses (n = 6/well; ± SD).