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Deletion of Smad4 mildly affects trabecular bone mass. (A,B) Picrosirius Red staining of longitudinal sections of the tibia. (C) μCT quantification of trabecular bone of the tibia. −DOX, mice raised on Dox from conception until P21, and then weaned off Dox for 9 weeks before harvest. +DOX, mice maintained on Dox from conception until harvest at the same age as the −Dox mice. *P<0.05, n=3.
