Table 1. General characteristics of the discovery and validation populations.
| Characteristic | Discovery stage |
Validation population | ||
|---|---|---|---|---|
| Control group (n = 16) | Exposed group (n = 8) | p-Valueb | n = 489 | |
| General characteristics | ||||
| Age (years)a | 50.4 ± 6.4 | 48.3 ± 4.3 | 0.419 | 41.9 ± 8.3 |
| Gender (Male/Female) | 12/4 | 6/2 | 1.000 | 438/51 |
| BMI (kg/m2, mean ± SD)a | 25.0 ± 2.9 | 25.0 ± 4.9 | 0.986 | 23.9 ± 3.5 |
| No. of working years (years)a | – | 27.5 ± 5.3 | – | 21.1 ± 9.6 |
| Waist circumference (cm)a | 85.9 ±8.7 | 88.9 ± 11.5 | 0.480 | 83.4 ± 9.1 |
| Hip circumference (cm)a | 95.6 ± 4.7 | 97.8 ± 4.5 | 0.290 | 95.2 ± 7.8 |
| Waist hip ratioa | 0.90 ± 0.07 | 0.91 ± 0.08 | 0.784 | 0.87 ± 0.07 |
| Seated blood pressure (mm Hg)a | ||||
| Systolic blood-pressure | 134.4 ± 19.5 | 128.8 ± 18.1 | 0.499 | 118.9 ± 15.5 |
| Diastolic blood-pressure | 82.8 ± 11.4 | 85.0 ± 11.0 | 0.649 | 81.2 ± 10.8 |
| Smoking status (Yes/No) | 6/10 | 2/6 | 0.667 | 291/198 |
| Pack-years of smokinga | 21.1 ± 11.8 | 23.8 ± 11.6 | 0.785 | 19.0 ± 13.5 |
| Drinking status (Yes/No) | 5/11 | 0/8 | 0.130 | 184/305 |
| Exercise (Yes/No) | 7/9 | 4/4 | 1.000 | 208/276 c |
aValues are mean ± SD.
bp-Value determined by Student’s t-test for continuous variables and by Fisher’s Exact Test for categorical variables.
cInformation missing on exercise for 5 people.