Table V.

Univariate Cox models for patients with invasive breast cancer.

	OS			DFS
Characteristics	HR	95% CI	P	HR	95% CI	P-value
p85α overexpression vs. downregulation	3.06	1.13–8.31	0.028	2.68	1.30–5.54	0.008
miR-21 low vs. high	2.47	1.08–5.65	0.033	1.80	1.03–3.12	0.038
Clinical stage I vs. II vs. III	4.20	2.15–8.20	<0.001	3.59	2.35–5.50	<0.001
Tumor size (cm) ≤2 vs. >2	3.44	1.28–9.27	0.015	3.82	1.95–7.46	<0.001
Node negative vs. positive	5.38	2.00–14.45	0.001	3.76	2.02–6.98	<0.001
Histological grade 1 vs. 2 vs. 3	2.57	1.19–5.55	0.017	2.25	1.47–3.45	<0.001
Subtypes of breast cancer	1.25	0.77–2.04	0.371	1.01	0.72–1.43	0.944
ER negative vs. positive	0.63	0.25–1.59	0.327	0.95	0.46–1.97	0.891
PR negative vs. positive	0.96	0.36–2.58	0.933	1.19	0.57–2.46	0.646
HER2 negative vs. positive	0.70	0.20–2.39	0.577	0.99	0.48–2.07	0.991
Mastectomy vs. breast conservation	0.50	0.26–0.95	0.033	0.63	0.42–0.95	0.026
Neoadjuvant chemotherapy vs. adjuvant chemotherapy vs. not given	0.33	0.05–2.48	0.282	0.55	0.20–1.52	0.246

Italics indicate significance.

^aSample sizes differ due to complete data set per Cox model.