Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 6;113(3):656–661. doi: 10.1073/pnas.1509834113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 4. — Endothelial Wt1 expression is required for coronary vessel formation. (A and B) H&E-stained sections from control Wt1^LoxP/LoxP+Tamoxifen (A) and mutant Tie^CreERT2;Wt1^LoxP/LoxP+Tamoxifen (B) E16.5 embryos. (C–F) The WT1⁺ cell contribution to coronary vessels (arrows in C) is reduced in the mutants (D and E), and Wt1 gene expression in E16.5 mutant hearts is reduced (F). (G and H) E16.5 mutant embryonic hearts show a decrease in compact ventricular wall coronary CD31⁺ cells (arrow in H; compare with G). (I and J) Quantification of the area occupied by CD31⁺ cells (I) and CD31 gene expression (J) in E16.5 hearts. A, atrium; EPI, epicardium; V, ventricle. (Scale bars: 50 µm.) Data are mean ± SEM; *P < 0.05, ***P < 0.001.