Table 2.

RNA binding and ATPase activity of WT RIG-I and H830A RIG-I

	WT RIG-I		H830A RIG-I
RNA ligand	Kd,app, nM	katpase, s−1	Kd,app, nM	katpase, s−1
5′ppp HP RNA	1.8 ± 0.9	33 ± 0.9	1.6 ± 1.9	34 ± 1
5′ppp 2′-OMe HP RNA	40 ± 6	12 ± 0.4	2.3 ± 0.7	32 ± 0.5
Cap-0 HP RNA	1.7 ± 0.5	25 ± 0.4	1.9 ± 0.5	22 ± 0.4
Cap-1 HP RNA	425 ± 50	15 ± 0.7	9.5 ± 2	24 ± 0.3