Fig. 2.
Expression analysis of SDPR in clinical samples and model cell lines. (A) SDPR mRNA levels in metastatic MIV cells compared with nonmetastatic MII (P = 0.00047) and MIII (P = 0.0005) cells. (B) Endogenous SDPR protein levels in the model cell lines were assessed by Western blot. (C) In silico Kaplan–Meier analysis depicting the association between SDPR expression and distant-metastasis–free survival (DMFS). The analysis was run on a cohort with 1,211 breast cancer patients, P = 0.0086. (D) In silico Kaplan–Meier analysis depicting the association between SDPR expression and relapse-free survival (RFS). The analysis was run on a cohort with 2,785 breast cancer patients, P = 1.1e-10. *P < 0.05.