Table 4.
Distribution of the ALDH2 polymorphism genotypes, alleles, and analysis of the genetic model
| Groups | Genotype, n (%) | Allele, n (%) | Dominant model | Recessive model | ||
|---|---|---|---|---|---|---|
| GG + GL | LL | G | L | (GL+LL)/GG | LL/(GL+GG) | |
| Control (n = 900) | 719 (79.89) | 181 (20.11) | 1232 (68.44) | 568 (31.56) | 387:513 | 181:719 |
| NAFLD (n = 900) | 717 (79.67) | 183 (20.33) | 1226 (68.11) | 574 (31.89) | 391:509 | 183:717 |
| OR* | 1.0000 | 1.0138 | 1.0000 | 1.0155 | 1.0182 | 1.0138 |
| 95% CI | 0.4079–1.4825 | 0.5372–1.5285 | 0.5017–1.4720 | 0.4079–1.4825 | ||
| P | 0.1294 | 0.0948 | 0.0865 | 0.1294 | ||
*Adjusted by sex, age, and smoking status. ALDH2: Aldehyde dehydrogenase 2; NAFLD: Nonalcoholic fatty liver disease; CI: Confidence interval; OR: Odds ratio.