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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Chem Asian J. 2015 Sep 4;10(10):2084–2094. doi: 10.1002/asia.201500434

Figure 4.

Figure 4

A) Schematic of the design and assembly of DNA micelles. (Top) Oligonucleotide micelles contain a DNA corona, a pyrene unit (fluorescence reporter), and a lipid core. (Bottom) Molecular structure of pyrene and lipid unit.[29b] Copyright 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim B) Structure of aptamer-coated PLGA hybrid nanoparticles and co-delivery of two drugs to cancer cells. PTX is encapsulated in the PLGA core and DOX is loaded in the lipid-PEG-aptamer shell. Lecithin and DSPE-PEG are used to stabilize the structure. Reprinted by permission from reference.[30] Copyright 2015 Royal Society of Chemistry.

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