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. Author manuscript; available in PMC: 2016 Jan 25.
Published in final edited form as: Hum Mutat. 2014 Mar 6;35(6):728–737. doi: 10.1002/humu.22524

Figure 2. Amplification of MDM4 or MDM2 genes in specific cancers can result in decreased patient survival.

Figure 2

Gene copy number alterations and survival data were obtained from the cBioPortal for Cancer Genomics (http://www.cbiopor2tal.org/public-portal/) July 2013 (Cerami, et al., 2012; Gao, et al., 2013). Kaplan-Meier survival curves of patients with (A) uterine carcinoma with and without MDM4 amplification and (B) glioblastoma with and without MDM2 amplification. The number (n) of samples of each is indicated, and p values were calculated by log-rank tests comparing survival between groups.