Table 2.

Statistical analysis of GABHS infections in group treated with SsK12 and in control group during 90-day therapy

	Subjects
Group SsK12	76
Control	54
General data				Approach A			Approach B			Odds ratio
				Analysis without multiplicity			Analysis with multiplicity
Analysis performed on the number of events with contingency analysis Fisher’s exact test				Analysis performed on the number of events with contingency analysis Fisher’s exact test			One-way mean Mann–Whitney nonparametric test
Group	No event	1 event	2 or more events	Group	1 or more events	No event	Group	Number	Media
SsK12 12 months	67	6	3	SsK12 12 months	9	67	SsK12 12 months	76	0.14	0.03 (0.02±0.11)
Control 12 months	12	36	6	Control 12 months	42	12	Control 12 months	54	0.88
P<0.001				P<0.001			P<0.001

Abbreviations: GABHS, group A beta-hemolytic streptococci; SsK12, Streptococcus salivarius K12.