Table 3.
Statistical analysis of GABHS infections in group treated with SsK12 and in control group during 9 months of observation after therapy
| Subjects | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Group SsK12 | 76 | |||||||||
| Control | 54 | |||||||||
|
| ||||||||||
| General data
|
Approach A
|
Approach B
|
Odds ratio | |||||||
| Analysis without multiplicity
|
Analysis with multiplicity
|
|||||||||
| Analysis performed on the number of events with contingency analysis Fisher’s exact test
|
Analysis performed on the number of events with contingency analysis Fisher’s exact test
|
One-way mean Mann–Whitney nonparametric test
|
||||||||
| Group | No event | 1 event | 2 or more events | Group | Events | No event | Group | Number | Media | |
| SsK12 12 months | 65 | 9 | 2 | SsK12 12 months | 11 | 65 | SsK12 12 months | 76 | 0.22 | 0.07 (0.03±0.16) |
| Control 12 months | 15 | 23 | 16 | Control 12 months | 39 | 15 | Control 12 months | 54 | 1.1 | |
| P<0.001 | P<0.001 | P<0.001 | ||||||||
Abbreviations: GABHS, group A beta-hemolytic streptococci; SsK12, Streptococcus salivarius K12.