Table 2. Time-related results within and between groups.
Values are expressed as mean with 95% confidence interval (95%CI).
| PLACEBO (n = 28) | INTERVENTION (n = 34) | p for between-group difference | |||||
|---|---|---|---|---|---|---|---|
| Baseline | After 12 months of treatment | Baseline | After 12 months of treatment | ||||
| Mean (95%CI) | Mean (95%CI) | p | Mean (95%CI) | Mean (95%CI) | p | ||
| Phosphate (mmol/L) | 1.19 (1.11–1.28) | 1.29 (1.19–1.40) | 0.01 | 1.27 (1.14–1.39) | 1.35 (1.18–1.51) | 0.26 | 0.07 |
| oxLDL (U/L) | 60.2 (53.9–66.5) | 63.4 (56.6–70.1) | 0.03 | 66.8 (62.1–71.4) | 55.1 (62.1–71.4) | <0.001 | <0.001 |
| LDL (mmol/L) | 3.2 (2.9–3.6) | 3.4 (3.0–3.7) | 0.22 | 3.8 (3.5–4.2) | 2.6 (2.3–2.9) | <0.001 | <0.001 |
| MDA (μmol/L) | 7.7 (7.1–8.2) | 8.0 (7.6–8.5) | 0.10 | 7.7 (7.2–8.1) | 7.8 (7.4–8.2) | 0.38 | 0.37 |
| eGFR (mL/min/1.73m2) | 38 (32–43) | 37 (31–43) | 0.30 | 33 (29–38) | 32 (27–37) | 0.10 | 0.60 |
| cFGF23* (RU/mL) | 150.0 (90.8–236.8) | 145.0 (95.0–359.0) | 0.001 | 181.0 (130.0–310.5) | 179.0 (137.8–318.0) | 0.14 | 0.33 |
| α-Klotho (pg/mL) | 483.2 (427.9–538.5) | 489.6 (443.0–536.3) | 0.62 | 476.9 (433.6–520.3) | 492.7 (448.6–536.7) | 0.23 | 0.62 |
| Urinary phosphate (mmol/L) | 12.3 (10.0–14.6) | 12.4 (9.8–15.0) | 0.97 | 11.6 (8.8–14.4) | 9.3 (7.7–11.0) | 0.02 | 0.32 |
* cFGF23 is expressed as median and interquartile range.