Table 3. The effect of anti-oxidant treatment on α-Klotho in a multivariable GEE analysis.
| Intervention versus placebo (change in pg/ml α-Klotho) | β (95% CI) |
|---|---|
| Crude | -1.6 (-62.5–59.3) |
| Model 11 | 8.4 (-53.8–70.6) |
| Model 22 | 3.6 (-62.8–70.0) |
| Model 33 | 8.9 (-71.5–89.4) |
1 Model 1: Adjusted for time course, MDRD
2 Model 2: Adjusted for variables from Model 1, plus an interaction term between group and time
3 Model 3: Adjusted for all variables from Model 2 plus 25OH-vitamin D, cFGF23, PTH, phosphate, calcium