Skip to main content
. 2016 Jan 21;12:219–227. doi: 10.2147/NDT.S90960

Figure 3.

Figure 3

Effect of chronic GEBR-7b treatment on expression of PKAca, pCREB, CREB, and GLT1 in the hippocampus of rats.

Notes: (A) Representative immunoblots of PKAca, pCREB, CREB, and GLT1 detected by Western blotting with tissues from the hippocampus; the rest of the panels are the quantification of the immunoblotting bands of PKAca (B), pCREB (C), CREB (D), and GLT1 (E). Data shown are mean ± SEM of eight animals/group and were analyzed using one-way ANOVA followed by Newman–Keuls tests. *P<0.01 vs nonstressed rats treated with vehicle; **P<0.01 vs stressed rats treated with vehicle.

Abbreviations: PKAca, protein kinase A catalytic subunit; pCREB, phosphorylation of cAMP response element-binding; CREB, cAMP response element-binding; GLT1, glutamate transporter 1; cAMP, cyclic adenosine monophosphate; CUS, chronic unpredictable stress; SEM, standard error of the mean.