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. Author manuscript; available in PMC: 2016 Jan 25.
Published in final edited form as: Pediatr Infect Dis J. 2013 Mar;32(3):e99–e104. doi: 10.1097/INF.0b013e31827bd619

TABLE 5.

Respiratory virus co-infection in patients with URTI and LRTI

Viruses URTI LRTI P
n=156 n=37
1 virus 121(78) 25 (68) 0.21
HRV 70 (58) 15 (60)
hCoV 11 (9) 0 (0)
hBoV 0 (0) 3 (12)
PIV 13 (11) 2 (8)
RSV 13 (11) 3 (12)
Influenza 7 (6) 1 (4)
hADV 4 (3) 0 (0)
hMPV 3 (2) 1 (4)

Co-infection
2 viruses
27 (17) 9 (24) 0.35
HRV+PIV 8 (30) 2 (22)
HRV+ hBoV 2 (7) 2 (22)
HRV+ Influenza 3 (11) 0 (0)
HRV+ hCoV 3 (11) 1 (11)
HRV +RSV 3 (11) 1 (11)
Influenza + hBoV 2 (7) 0 (0)
Co-infection
>2 viruses
8 (5) 3 (8) 0.44
hBoV+hCoV+RSV 1 (<1) 1 (<1)
hBov+HRV+hMPV 0 (0) 1 (<1)

Data are no. (%) of patients, unless otherwise indicated. ARI, acute respiratory illness; URTI, upper respiratory tract infection; LRTI, lower respiratory tract infection; HRV, human rhinovirus; hCoV, human coronavirus; hBoV, human bocavirus; hEV, human enterovirus; PIV, parainfluenza virus; RSV, respiratory syncytial virus; hADV, human adenovirus; hMPV, human metapneumovirus.

Only combinations with more than one virus in each group are shown. No bacterial or fungal pathogens were identified with the co-infections.