. 2016 Jan 25;11(1):e0147571. doi: 10.1371/journal.pone.0147571

Table 1. Peptide pairs with significant median differential magnitude of response Δ DR-WT ^a.

WT peptide	Magnitude of response to WT peptide [Median (range); SFC/10⁶ PBMC]	DR peptide	Magnitude of response to DR peptide [Median (range); SFC/10⁶ PBMC]	Median Δ DR-WT response (SFC/10⁶ PBMC)	HIV Gene	DR mutation	p value
RNLLTQIGC	0 (0–140)	RNLMTQIGC	130 (51–450)	120	PR	L90M	0.0009
QHLLRWGLT	0 (0–62)	QHLLRWGLY	115 (60–200)	110	RT	T215Y	0.0005
DTVLEEMNL	29 (0–200)	DTVIEEMNL	130 (60–380)	80	PR	L33I	0.0020
KMIGGIGGFI	0 (0–163)	KMIGGVGGFI	80 (51–163)	70	PR	I50V	0.0039
EKEGKISKI	72 (56–190)	EKDGKISKI	0 (0–113)	-66	RT	E44D	0.0195
KKSVTVLDVGDAYFS	123 (51–930)	NKSVTVLDVGDAYFS	0 (0–890)	-70	RT	K103N	0.0078
EELRQHLLRW	80 (0–164)	EELRQHLWRW	0 (0–60)	-80	RT	L210W	0.0007
KKSVTVLDVGDAYFS	123 (51–930)	KKSMTVLDVGDAYFS	0 (0–690)	-90	RT	V106M	0.0313
NLLTQIGCT	170 (0–484)	NLMTQIGCT	0 (0–238)	-168	PR	L90M	0.0005

^a Wilcoxon Signed Rank Test. Positions associated with drug resistance are shown in bold.

Table 1. Peptide pairs with significant median differential magnitude of response Δ DR-WT a.