Table 1. Association between FAS rs2234767, rs1800682 and FASLG rs763110 genotypes and risk of CRC.

SNPs	Genotype	Cases (n = 878)		Controls (n = 884)		Pa	Pb	Adjusted OR (95% CI)c
		n	%	n	%
FASLG	CC	462	53	470	53	0.71	1.0	1.00 (Ref)
rs763110	CT	354	40	344	39			1.06 (0.87–1.28)
	TT	62	7	70	8			0.90 (0.62–1.30)
	Ptrend							0.92
	T allele	478	27	484	27	0.92	1.0
FAS	GG	305	37	385	44	0.0051	0.015	1.00 (Ref)
rs2234767	GA	407	49	372	43			1.39 (1.13–1.71)
	AA	124	15	114	13			1.37 (1.02–1.84)
	Ptrend							0.0051
	A allele	655	39	600	34	0.0042	0.013
	GG	305	36	385	44			1.00 (Ref)
	GA/AA	531	64	486	56			1.38 (1.14–1.68)
FAS	AA	301	34	348	40	0.060	0.18	1.00 (Ref)
rs1800682	AG	435	50	392	44			1.30 (1.06–1.60)
	GG	142	16	144	16			1.16 (0.88–1.53)
	Ptrend							0.14
	G allele	719	41	680	38	0.13	0.39
	AA	301	34	348	39			1.00 (Ref)
	AG/GG	577	66	536	61			1.26 (1.04–1.53)

Bold indicated statistically significant.

^aχ² test for either genotype distributions or allele frequencies between the cases and controls.

^bAdjusted for multiple comparisons by Bonferroni correction.

^cAdjusted for age, sex, smoking and drinking status in logistic regression model.