Table 1. Top 20 hits identified in 32 male subjects (16 AUD cases vs. 16 controls).

CpGs	Chr.	Position	Genes	Locationa	βb	Effectc	Pnominald	qe
cg19099433	2	3748379	ALLC	Body	0.92	−0.03	9.5 × 10−9	0.002
cg16460727	5	175297349	CPLX2	Promoter	0.87	−0.04	2.9 × 10−7	0.035
cg11938646	17	27050355	SNORD42A	Promoter	0.77	0.07	7.0 × 10−7	0.038
cg10767665	19	44279027	KCNN4	Body	0.17	0.05	9.6 × 10−7	0.038
cg05764102	16	72991344	ZFHX3	Promoter	0.91	−0.03	1.8 × 10−6	0.038
cg11562309	7	94286473	PEG10	Promoter	0.47	0.04	1.9 × 10−6	0.038
cg11415275	1	146715872	CHD1L	Body	0.13	0.05	2.6 × 10−6	0.038
cg09244748	11	63532530	C11orf95	Body	0.68	0.07	2.7 × 10−6	0.038
cg14250274	7	66206258	RABGEF1	Promoter	0.09	0.04	2.7 × 10−6	0.038
cg15836231	6	91490663		Intergenic	0.92	0.04	3.5 × 10−6	0.038
cg09249675	19	3401572	NFIC	Body	0.86	0.06	4.9 × 10−6	0.038
cg11344164	10	101878520		Intergenic	0.87	−0.05	5.5 × 10−6	0.038
cg14932133	2	121739247	GLI2	Body	0.90	−0.04	6.3 × 10−6	0.038
cg16695999	5	93905343	C5orf36	Promoter	0.81	0.05	6.5 × 10−6	0.038
cg17865555	19	49133647	SPHK2	3′UTR	0.26	0.10	7.0 × 10−6	0.038
cg13556266	4	8696173		Intergenic	0.83	−0.06	7.6 × 10−6	0.038
cg00147578	12	120730932		Intergenic	0.17	0.04	7.8 × 10−6	0.038
cg03064005	11	68142768	LRP5	Body	0.82	−0.07	8.3 × 10−6	0.039
cg07881365	19	15833929		Intergenic	0.29	0.08	8.8 × 10−6	0.039
cg06122518	1	168356673		Intergenic	0.20	0.06	9.4 × 10−6	0.039

^aLocation of CpGs in promoter regions, gene bodies, or 3′ untranslated regions (3′ UTRs).

^bAverage CpG methylation levels.

^cLog-scale fold changes obtained by the R package limma.

^dP values obtained by the R package limma.

^eq values obtained by multiple testing controlling FDR at 0.05.