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. 2016 Jan 18;6:19360. doi: 10.1038/srep19360

Figure 1. TNFα and IL-6 synthesis and secretion from peritoneal macrophages isolated from PC1/3 KO mice under CpG-ODN challenge.

Figure 1

Under CpG-ODN challenge, peritoneal macrophages isolated from PC1/3 KO mice synthesize (a) and secrete (b) more TNFα than those harvested from WT mice. Similar results were obtained for IL-6 production (c) and secretion (d). Peritoneal macrophages were stimulated for 4 h with 1 μM CpG-ODN 2006 and TNFα or IL-6 concentration was measured using an ELISA kit. The data represent the mean ± SE. (n = 4; *p < 0.05; **p < 0.01 as determined by the t-test).