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. 2016 Jan 19;6:19386. doi: 10.1038/srep19386

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Copyright © 2016, Macmillan Publishers Limited

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Genes were selected based on a P-value > 0.05 and a FC > 1.5 fold difference in expression with day 10 and day 14 MESP1-mCherry negative derivatives. (A) A selection of regulatory and functional genes that were enriched. Heatmaps show averaged values from n = 3. (B) Evidence for protein-protein interaction networks of the enriched transcription factors at day 10 and 14 of differentiation was constructed by STRING. Interactions with a medium confidence >0.4 are visualized. Proteins are clustered using the MCL algorithm. Every color represents a cluster. Inter-cluster edges are represented by dashed lines (C).