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. 2016 Jan 19;6:19309. doi: 10.1038/srep19309

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(A) SHAPE-derived MFE-2D-structures of all 5 transcripts in their editosome-bound conformation. U-nt within the top 10% of responsive nt-positions are shown in green (increased SHAPE-reactivity) and blue (decreased SHAPE-reactivity). Black: non-uridine responsive nt. (B) Circle plot representations of the SHAPE-derived 2D-structures of the 5 pre-mRNAs. Base pairs are shown as colored lines. Green: basepairs present in both RNA folding states. Red: basepairs unique to the editosome-bound RNA conformations. Black: basepairs unique to the free RNA folding states. Plots were generated using CircleCompare of RNAstructure²⁶.