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. 2016 Jan 19;6:19309. doi: 10.1038/srep19309

Table 1. Summary of the thermodynamic folding characteristics of mitochondrial pre-mRNAs in their free and editosome-bound RNA folding state.

    pre-mRNA
RPS12pe ND3pe A6pe CYbme COIne
In silico ΔGRNAStructure −102 −98 −98 −344 −468
ΔGViennaRNA −103 −107 −107 −336 −459
RNAfree ΔGSHAPE −152 −137 −137 −496 −823
ΔG/nt −0.45 −0.37 −0.34 −0.41 −0.48
ΔG/bp −1.46 −1.35 −1.59 −1.27 −1.47
r(ntbp/ntss) 0.62 0.57 0.47 0.64 0.66
RNAed.-bound ΔGSHAPE −127 −124 −113 −407 −725
ΔG/nt −0.38 −0.33 −0.28 −0.33 −0.43
ΔG/bp −1.39 −1.23 −1.62 −1.09 −1.39
r(ntbp/ntss) 0.54 0.55 0.37 0.61 0.61
ΔΔG 25 14 23 89 98
ΔΔG/nt 0.08 0.04 0.06 0.07 0.06
ΔΔG/bp 0.07 0.12 −0.03 0.17 0.08
Δntbasepaired (%) −7.7 −2.7 −10.1 −3.1 −4.5
bp preserved (%) 84 82 50 55 52

∆G-values are in kcal/mol. pe: pan-edited, me: marginally edited, ne: never edited.