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. 2016 Jan 19;6:19636. doi: 10.1038/srep19636

Figure 3. Mb-scale single DNA molecules reveal clusters of closely spaced fired origins.

Figure 3

We plotted the cumulative frequencies of inter replication track distances (IRTDs) measured by Patel et al., 2006 (dark grey squares), the IRTDs measured on full length molecules analysed in our study (black triangles), and the same molecules analysed in our study but “cut” in silico to shorter 500 Kb fragments (light grey circles). The “cut” fragments show a similar distribution of IRTDs as the molecules analysed by Patel et al., 2006, indicating that the failure to detect clusters of closely spaced origins previously was due to the relatively short size of single DNA molecules analysed.