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. 2016 Jan 22;6:19603. doi: 10.1038/srep19603

Table 5. Leukocytosis and ORs for VTE among newly diagnosed lung cancer patients.

Patients Group Leukocytosis1 OR(95%CI)
Number of patients (%) Unadjusted Adjusted2 Adjusted3
No hypertension and no VTE 63(13.6) 1 1 1
Only hypertension 11(13.1) 0.95(0.48–1.90) 0.87(0.42–1.79) 0.90(0.43–1.88)
Only VTE 20(30.8) 2.82(1.56–5.08) 3.51(1.67–5.96) 3.21(1.69–6.08)
Both hypertension and VTE 4(19.0) 1.49(0.49–4.57) 1.33(0.41–4.39) 1.33(0.41–4.36)
P for trend 0.006 0.006 0.011 0.009

1Leukocytosis was defined as WBC count of at least 10 × 109/L.

2Adjusted for age, gender, smoking, body mass index, diabetes, dyslipidemia, and tumor histology (adenocarcinoma vs. non-adenocarcinoma).

3Adjusted for age, gender, smoking, body mass index, diabetes, dyslipidemia, and tumor stage (localized stage vs. distant metastasis).

Abbreviations: VTE = venous thromboembolism; OR = Odds Ratio; WBC = white blood cell.