Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 20;6:19579. doi: 10.1038/srep19579

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) Representative photomicrographs of SN sections immunostained for TH from normal rat, PD rat, GDNFp-cMB+FUS group, and cMB+FUS+GDNFp group. (B) IHC distribution of GDNF, GFAP, and Tuj1 expression in the sonication region after gene transduction. Transfected GDNF/GFAP/DAPI (top) and GDNF/Tuj1/DAPI (bottom) for the normal rat, PD rat, and PD GDNFp-cMB+FUS group, respectively. GDNF: red; Tuj1: green; GFAP: green; DAPI: blue. (C) The optical density of TH fibers in the lesioned hemisphere compared to the non-lesioned hemisphere. (D) The fluorescence intensity of GDNF, GFAP and Tuj1 in the lesioned site compared to the normal rat. Single asterisk, p < 0.05; double asterisk, p < 0.01. Data were analyzes by one-way ANOVA (post hoc test: Dunnett; degrees of freedom: 8, 6; F value: 46.9, 39.2) and presented as mean ± SEM (n = 6 per group). All of the data were compared with PD untreated rats.